GWAS Catalog (EBI)

Base URL

https://www.ebi.ac.uk/gwas/rest/api

Auth

No API key required.

Note: Responses use HAL+JSON format with `_links` and `_embedded` keys.

Key Endpoints

Endpoint	Description
`/studies/{accession}`	Single study (e.g. GCST001633)
`/studies/search/findByPubmedId?pubmedId={id}`	Studies by PubMed ID
`/singleNucleotidePolymorphisms/{rsId}`	SNP details
`/singleNucleotidePolymorphisms/{rsId}/associations`	Associations for a SNP
`/singleNucleotidePolymorphisms/search/findByRsId?rsId={rsId}`	Search by rsID
`/associations`	List associations
`/associations/{id}`	Single association
`/efoTraits`	List EFO traits
`/efoTraits/search/findByEfoTrait?trait={name}`	Search traits

Pagination

?page=0&size=20 (zero-indexed, max ~500)

Example Calls

# Get a study
https://www.ebi.ac.uk/gwas/rest/api/studies/GCST001633

# Associations for a SNP
https://www.ebi.ac.uk/gwas/rest/api/singleNucleotidePolymorphisms/rs7329174/associations

# Search traits
https://www.ebi.ac.uk/gwas/rest/api/efoTraits/search/findByEfoTrait?trait=diabetes&page=0&size=5

Response Format

HAL+JSON. Results in _embedded.studies[] or _embedded.associations[]. Key fields: pvalue, riskFrequency, orPerCopyNum, betaNum.

Rate Limits

No published limit. Bulk data via FTP at ftp.ebi.ac.uk/pub/databases/gwas/